Aloe-emodin aloe leaves plant extract powder CAS 481-72-1,China Real price supplier

Aloeemodin, Aloe-Emodin Extract, Aloe Extract, barbaloin

Product name: Aloe-emodin extract  

CAS No. 481-72-1

Molecular formula: C15H10O5

Molecular weight: 270.24

Odor: Characteristic

Purity: 98%,99% Aloe-emodin 

Appearance: Orange powder

Extraction type: Solvent extraction

Grade: Pharmaceutical and food

Aloe-emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, 

has a specific in vitro and in vivo antineuroectodermal tumor activity. 

The growth of human neuroectodermal tumors is inhibited in mice with severe combined immunodeficiency without any appreciable toxic effects on the animals. The compound does not inhibit the proliferation of normal fibroblasts nor that of hemopoietic progenitor cells. 

The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energy-dependent pathway of drug incorporation. 

Taking into account its unique cytotoxicity profile and mode of action, AE might represent a conceptually new lead antitumor drug.

Function

1.Anti-tumor activity, Aloe-emodin on the inhibition of P388 leukemia cells and prolong survival. One of the mechanisms is the inhibition of cancer cell DNA, RNA and Protein biosynthesis.

2. Antibacterial activity.

3. Immunosuppression. Aloe-emodin can inhibit the organisms immune response, inhibition of carbon clearance ability, to reduce the weight of immune organs, reduced white blood cell count, decreased macrophage function. 100μg/ml oncentration in vitro [3H]-TDR and [3H] Urd into the cell parameters significantly inhibited.

4. Purgative activity . Aloe-emodin has a strong purgative activity of intestinal bacteria metabolism aloe emodin, rhein, rhein anthrone,which has a strong purgative effect.

Application of Emodin 

1.Applied in food field,it's used as Food Additive with the function of  lengthening life

2.Applied in pharmaceutical field,it's frequently used as medicine supplement or OTCS ingredients and owns good efficacy for treatment of cancer and cardio-cerebrovascular disease

3.applied in comestics,it's can delay aging and prevent UV radiation

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What is Aloe Vera Extract?  

The active constituents for aloe's laxative effect are known as anthraquinone glycosides, which are converted by intestinal bacteria into aglycones. The active compounds responsible for aloe's wound healing properties are less well-described but are likely a combination of several saccharide molecules. When the leaf is consumed, the high fiber content of the plant has been shown to exert beneficial effects on cardiac disease risk factors by reducing blood levels of cholesterol, triglycerides and glucose.

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Aloeemodin, Aloe-Emodin Extract, Aloe Extract, barbaloin