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1), Chinese name: Almond glycoside
2), English name: amygdalin
3), Alias: Amygdalin Mandelonitrile-β -gentiobioside, Amygdaloside, Laetrile, VB-17
4), Chemical name: Benzeneacetonitrile, α -[(6-O-β -D-glucopyranosyl-β -D-glucopyranosyl) oxy] -,
5), (R) - Latin name: Semen armeniacae amarum
6), CAS No: : 29883-15-6
7), Specifications: 98% /99% (HPLC)
8), Molecular formula: C20H27NO11;
9), Molecular: 457.42
10), Physical properties: Trihydrate orthorhombic columnar crystal (water), melting point 200 ° ; Anhydrous melting point of about 20 ° , [α ] 20D-42 ° . LG dissolved in 12ml of water, 900ml ethanol and 11ml boiling alcohol, easily soluble in boiling water, almost insoluble in diethyl ether. UVλ MeOHmax nm: 268 (179), 262 (255), 257 (256), 251198), 208 (7210); IRν Max cm - 1: 3330, 2860, 1640, 1590, 1490, 1450, 1270, 1160, 1060, 690 [1].
11), Pharmacological effects: It started back in 1845 for the treatment of cancer, new home and abroad are nonvolatile memories. The mechanism different opinions, some people think that its anti-cancer effect is due to carcinoma of Acid β -glucosidase enzyme in 1 - mandelic nitrile-β -glucuronidase HCN generated due to death, also reported that the anti-cancer effect was mainly due to nitrile instead of almond caused by cyanide. Japan and the U. S. Reported a significant clinical effect of the treatment of cancer, but also reports and the results are also inconsistent, or opposite, and a post-service deaths. Therefore, the value of their cancer is still controversial.