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Andrographis Paniculata Extract
Product Name: Andrographis Paniculata Extract
Botanical Name: Andrographis paniculata(Burm.f.)Nees
Main components: Andrographolide
Part Used: Stem & Leaf
Specification: 90% ,50% ,10% , 5%
CAS No：5508-58-7
Molecular Formula: C20H30O5
Molecular Weight: 350.4492
Detection: HPLC
Appearance: White Powder
Introduction:
Andrographis paniculata, the Kalmegh of the Ayurveda, is an erect annual herb extremely bitter in taste in each and every part of the plant body. The plant is known in north-eastern India as ‘Maha-tita’, literally ‘king of bitters’, and known by various vernacular names . It is also known as ‘Bhui-neem’, since the plant, though much smaller in size has a similar appearance and has the same bitter taste as that of Neem (Azadirachta indica). In Malaysia, it is known as 'Hempedu Bumi' literally means 'bile of earth' since it is one of the most bitter plants that are used in traditional medicine. In Tamil it is called 'Sirunangai' or 'Siriyanangai'. The genus Andrographis consists of 28 species of small annual shrubs essentially distributed in tropical Asia. Only a few species are medicinal, of which Andrographis Paniculata is the most popular.
The plant is well known in Bengal by the name 'Kalmegh'. It is a principal herb in the domestic medicine called 'Alui', which is given to infants. Both in Ayurveda and Unani, it is confused with 'Chitetta' (Swertia chirata), but both are different plants. It is widely available in Arabia. It is mentioned in the official pharmacopoeia of India.. It is given for fever along with several herbs. It was advertised in England as a substitute for quinine.
Andrographis Paniculata is traditionally known as kalmegh. The plant belongs to family Acanthaceae and is widely used in Ayurvedic and Homeopathic systems of medicine. The plant grows in waste grounds and prefers moist habitat. The herb is bitter in taste and has weak odour. The whole plant may be used in medicine. It is widely cultivated in southern Asia, where it is used to treat infections and some diseases, often being used before antibiotics were created. Mostly the leaves and roots were used for medicinal purposes
Function:
1 Andrographis compounds have shown antivirus properties which appear to inhibit glycoprotein's in the virus. This impedes the viruses ability to invade cells in the body and replicate. It's andrographolide are currently being studied for the antiviral effects they have on avian bird flu virus, ebola virus and HIV.
2 There appears to be a significant presence of flavanoids in the Andrographis Paniculata herb, which always have an anti-inflammatory affect. In vitro studies have shown that the flavinoid activities supressed the genetic expression of neutrofils, an inflammatory agent. Similarly, studies have indicated that a variety of inflammatory proteins, including COX-2, are reduced by the presence of Andrographoloid.
3 In vitro andrographolide studies indicate an immuno-stimulating activity as well as a marked inhibitory effect. Its presence increases proliferation of lymphocytes and production of interleukin2, TNF-alpha production and cytotoxic activity of lymphocytes against certain cancer cell lines, as well as demonstrating potential direct anti-cancer activity by the induction of cell-cycle inhibitory protein p27 and decreased expression of cyclin-dependent kinase.
Application :
1 Colds, Flu & Sinusitis
2 Digestive problems
3 Cardiovascular
4 Anti-tumor