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Natural Medicine API Anti-bacterial & Anti-viral Annual Artemisia Extract Artemisinin
Annual Artemisia Extract
Product Name: Annual Artemisia Extract
Botanical Name: Artemisia annua L.
Main components: Artemisinin
Part Used: Leaf
Specification: 8:1
CAS No：63968-64-9
Molecular Formula: C15H22O5
Molecular Weight: 282.3322
Appearance: White Acicular Crystals
Introduction:
Artemisia annua, also known as sweet wormwood, sweet annie, sweet sage wort or annual wormwood , is a common type of wormwood native to temperate Asia, but naturalized throughout the world.
In 1971, scientists demonstrated the plant extracts had antimalarial activity in primate models, and in 1972, the active ingredient, artemisinin (formerly referred to as arteannuin), was isolated and its chemical structure described. Artemisinin may be extracted using a low boiling point solvent, such as diethylether, and is found in the glandular trichomes of the leaves, stems, and inflorescences, and it is concentrated in the upper portions of plant within new growth
Function:
Artemisinin is a kind of effective antimalarial drug being extracted from Artemisia annual, in which the artemisinin concentration is very low. So increasing artemisinin concentration is a hotspot in the research field, and it will be possible that biotechnology is applied to the study of Artemisia annual. It involved the following three aspects. First, DNA molecular marker assisted breeding. The genetic diversity of Artemisia germplasm was analyzed by the molecular maker, which provided the molecular biology basis for accelerating the breeding time of fine varieties with high artemisinin concentration. Second, artemisinin concentration was increased by genetic engineering. By transgenic technology overexpressing the key genes in artemisinin biosynthesis directly promoted the accumulating of artemisinin; inhibiting the expression of the gene, which competed with the genes in artemisinin biosynthesis for reduction substrate, indirectly increased the artemisinin concentration. Third, through synthetic biology method artemisinin precursor or artemisinin was produced in the host.
Application:
Effective for malaria that has developed drug resistance of chloroquine.
Restrain plasmodium growth and directly kill plasmodium.
Anti-inflammatory and canker.
Relieve cough and asthma.