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Polyphenol Type-A Polymers from Cinnamon Bark water Extracted powder with Insulin-like Biological Activity.
Our product, Cinnamon extract is a water-soluble polymeric
compounds extracted from Cinnamon bark. a full-spectrum liquid herbal extract made from the bark of Cinnamon (Cinnamomum (verum) zeylanicum)
Scientists at the Agricultural Research Service have found polyphenolic polymer compounds from cinnamon bark
that could become natural ingredients in products aimed at lowering blood sugar levels.
Recent studies demonstrate that water-soluble polymeric compounds isolated from cinnamon have insulin-enhancing
biological activity in the in vitro assay measuring the insulindependent effects on glucose metabolism and also
function as antioxidants.
The causes and control of type 2 diabetes mellitus are not clear, but there is strong evidence that
dietary factors are involved in its regulation and prevention. We have shown that extracts from
cinnamon enhance the activity of insulin. The objective of some studya were to isolate and characterize
insulin-enhancing complexes from cinnamon that may be involved in the alleviation or possible
prevention and control of glucose intolerance and diabetes. Water-soluble polyphenol polymers from
cinnamon that increase insulin-dependent in vitro glucose metabolism roughly 20-fold and display
antioxidant activity were isolated and characterized by nuclear magnetic resonance and mass
spectroscopy. The polymers were composed of monomeric units with a molecular mass of 288. Two
trimers with a molecular mass of 864 and a tetramer with a mass of 1152 were isolated. Their
protonated molecular masses indicated that they are A type doubly linked procyanidin oligomers of
the catechins and/or epicatechins. These polyphenolic polymers found in cinnamon may function as
antioxidants, potentiate insulin action, and may be beneficial in the control of glucose intolerance
and diabetes. MHCP methylhydroxychalcone