Diosmetin,China ZH CHEMICAL price supplier

 CAS No.: 520-34-3

Appearance: Yellow Fine Powder
Used part : peel
Specification:30% 50% 90% 98% Diosmetin 10:1 20:1 
Odor: Characteristic
Molecular Formula: C16H12O6
Molecular Weight: 300.26 
Particle size: 100% pass 80 mesh
Test Method: HPLC/TLC

Diosmetin is a Natural  Flavonoid Compound.

It can souble in methanol ,ethanol and other solvents.

Diosmetin widely exsist in nature, mainly in the form of free type or Glucoside type .

It can be found in chrysanthemum, spearmint, Valeriana jatamansi and Lemon .

Not only the flavonoids are an important part of People daily diet, but Also Diosmetin has the function of  prevention of cancer which is as the deitary flavonoids in the chemical prevention of cancer is a hot topic of domestic and foregin schloars in recent years.

1. Antioxidant

Alzheimer's disease is the most common cognitive dysfunction in the elderly population. Over-production and accumulation of beta-amyloid peptide (Aβ) is considered to be the leading cause of Alzheimer's disease. Advanced glycation end products (AGEs) have a close interaction with Aβ, whereas AGEs and their receptors use intracellular reactive oxygen species to transmit signals. ChandlerD et al. [14] have shown that geranyl has the ability to remove these reactive oxygen species and can delay the production of AGEs and their receptors and are therefore considered to be a natural antioxidant.

2. Estrogen-like effect

Menopausal women endogenous estrogen secretion, will lead to osteoporosis, blood cholesterol, menopausal syndrome and a series of diseases. Synthetic estrogen as a substitute for such diseases have a certain degree of prevention and treatment. Human breast cancer cell MCF-7 is an estrogen-sensitive breast cancer cell, and intracellular estrogen receptors bind to a ligand with estrogenic activity to induce a series of hormone-dependent intracellular responses. Response to cell proliferation. YoshikawaM et al [16] used human breast cancer cell MCF-7 sensitization test to isolate flavonoids from coriander in vitro estrogen test, the test results show that geraniol in a certain concentration range of human breast cancer cells MCF-7 proliferation has a catalytic effect, half effect concentration of 2.9μmol / L.

3. Anti-Bacterial

Tuberculosis is a pulmonary infectious disease caused by Mycobacterium tuberculosis, where millions of people die each year from tuberculosis and continue to have new infections. How to improve the cure rate of tuberculosis and the development of new anti-tuberculosis drugs, has become a global health concern. In the Philippines, the clinical use of a traditional Chinese herbal medicine called trash wood to treat tuberculosis. LirioSB et al. [17] observed the in vitro antibacterial activity of the methanol extract of Tricholoma matsutake in order to further study the material basis of tufted wood for the treatment of tuberculosis. By comparing the minimum inhibitory concentration of linalin and other extracts on Mycobacterium tuberculosis H37Rv strain, it was found that the fungi contained the compound with antimicrobial activity, which provided the theoretical basis for the treatment of tuberculosis.

4.Anti-cancer

Liver cancer is currently the main clinical use of chemotherapy for patients with liver cancer treatment, but the chemotherapy drugs to kill cancer cells at the same time the host of the normal cells and the immune system have some damage. Cancer patients are often accompanied by decreased immunity after treatment leading to other infection complications. In recent years, the specificity and effectiveness of anti-tumor drug has become a hot research.

1. As food additive, lemon extract is widely used in the field of food and health products;
2. As the acid to speed up the horny update, lemon extractis widely used in the field of cosmetic;
3. As dietary supplements increased therapeutic function,lemon extract is widely used in fields of dietary supplement products;
4. As anti-blood clotting agent, lemon extract is widely used in pharmaceutical industry.