Name: Epimedium P.E
Active ingredients: Icariin
Appearance: Solid powder
Test method:HPLC
CAS No.: 489-32-7
Formula: C 33 H 40 O 15
Molecular Weight: 676.66
Density: 1.55 g/cm 3
Melting Point: 231-232 °C
Boiling Point :948.5 °C at 760 mmHg
Flash Point: 300.9 °C
Application: Enhance immune,improve sexual function
1 · Applied in pharmaceutical field, it is mainly used as pharmaceutical materail to treat asthenia
of kidney, impotence, spermatorrhea, prospermia, cold extremities, acroanesthesia or convulsion, etc.
2 · Applied in the field of health care products, it was used in capsules, health food, oral liquid, health
care wine and other alcoholic beverages,
which has good health-care effect on human cardiovascular and endocrine system, delaying aging.
Introduction
Icariin is a flavonol , a type of flavonoid . It is the prenyl acetylation of kaempferide 3,7- O -di glucoside . The compound is derived from several species of plants in the genus Epimedium ,which are commonly known as Horny Goat Weed or Yin Yang Huo. Extracts from these plants are reputed to produce aphrodisiac effects, and are commonly used in Chinese herbal medicine to enhance erectile function, as well as for several other indications.
It is thought that icariin is likely to be the primary active component of Epimedium extracts, as it has been shown to share several mechanisms of action with compounds used in Western medicine to treat impotence and improve sexual function. In particular, icariin has been demonstrated to act as a PDE5 inhibitor and to enhance the production of bioactive nitric oxide ,as well as mimicking the effects of testosterone . It also shows antioxidant , antidepressant and neuroprotective effects in animal studies, as well as stimulating osteoblast activity in bone tissue which has been linked to a possible therapeutic role in the treatment of osteoporosis .