GMP&BV Manufacturer supply Best Resveratrol,China ZSKY price supplier

 

Polygonum Cuspidatum Root Extract Resveratrol Bulk Powder

 

 

Product Name	Giant knotweed extract
Latin name	Polygonum cuspidatum Sieb.et Zucc.
Synonyms name	Polygonum cuspidatum P.E.
Main ingredient products	Resveratrol (CAS 501-36-0)
Specification	Resveratrol 5%-99% by HPLC
Molecular formula	C14H12O3
Molecular weight	228.24
Appearance	Off-white fine powder
Package	25Kg/drum(With double layer plastic bag inside and outside  the cardboard barrels)

 

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Introduction:   

Poly gonum cuspidatum is native to eastern Asia and widely distributed in China. 

Polygonum cuspidatum have been used in traditional Japanese and Chinese medicine 

to treat a wide range of afflictions, including fungal diseases, various skin inflammations,

 cardiovascular diseases and liver diseases.

Resveratrol, belongs to a class of polyphenolic compounds called stilbenes, are found

 largely in the skins of red grapes and root of Polygonum cuspidatum Sieb.

 

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Resveratrol

(3,5,4'-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin

produced naturally by several plants when under attack by pathogens such as bacteria or

fungi. Resveratrol is found in the skin of red grapes and in other fruits. However, RED WINE

contains very little of it, on the order of 0.1-14.3 mg/l. Resveratrol has also been produced

by chemical synthesis and by biotechnological synthesis (metabolic engineered  microorg

anisms) and is sold as a nutritional supplement derived primarily from Japanese knotweed.

 

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Resveratrol Effects:

 

1).Cardioprotective effects

 

Moderate drinking of red wine has long been known to reduce the risk of heart disease.

This is best known as “the French paradox”.

Studies suggest resveratrol in red wine may play an important role in this phenomenon.

 

2).Anti-diabetic effects

 

Studies have shown resveratrol possesses hypoglycemic and hypolipidemic effects in

both streptozotocin (STZ)-induced diabetes rats and STZ-nicotinamide-induced diabetes

rats. Resveratrol ameliorates common diabetes symptoms, such as polyphagia, polydipsia ,

and body weight loss. Other diabetic animal model studies by different researchers have

also demonstrated the antidiabetic effects of resveratrol.

 

3).Neuroprotective effects

 

In November 2008, researchers at the Weill Medical College of Cornell University reported

dietary supplementation with resveratrol significantly reduced plaque formation in animal

brains, a component of Alzheimer's disease and other neurodegenerative diseases. In mice,

oral resveratrol produced large reductions in brain plaque in the hypothalamus ( − 90%),

striatum ( − 89%), and medial cortex ( − 48%) sections of the brain. In humans, oral doses of

resveratrol thoretically may reduce beta amyloid plaque associated with aging changes in the

brain. Researchers theorize that one mechanism for plaque eradication is the ability of

resveratrol to chelate (bind) copper. The neuroprotective effects have been confirmed in

several animal model studies.

 

4).Anti-inflammatory effects 

 

The anti-inflammatory effects of resveratrol have been demonstrated in several animal model

studies. In a rat model of carrageenan-induced paw edema, resveratrol inhibited both acute

and chronic phases of the inflammatory process.

 

Similarly, preincubation with resveratrol decreased arachidonic acid release and COX-2

induction in mouse peritoneal macrophages stimulated with tumor promoter PMA, ROI, or

lipopolysaccharides (LPS). In an experimental Rabbit inflammatory arthritis model, resveratrol

showed promise as a potential therapy for arthritis. When administered to rabbits with induced

inflammatory arthritis, resveratrol protected cartilage against the progression of inflammatory

arthritis.

 

5).Antiviral effects 

 

Studies show resveratrol inhibits herpes simplex virus (HSV) types 1 and 2 replication by

inhibition of an early step in the virus replication cycle. In vivo studies in mice found resveratrol

inhibits or reduces HSV replication in the vagina and limits extravaginal disease. The skin of

resveratrol-treated animals showed no apparent dermal toxicity, such as erythema, scaling,

crusting, lichenification, or excoriation.  Studies also show resveratrol inhibits varicella-zoster

virus, certain influenza viruses, respiratory viruses, and human cytomegalovirus. Furthermore,

resveratrol synergistically enhances the anti-HIV-1 activity of several anti-HIV drugs.

 

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Packing:

Packaging Description	Sealed export grade drum & double of sealed plastic bag  or according to your need
Storage	Stored in a cool and dry well-closed container kept away  from moisture and strong light or high temperature.
Shelf life	Two years under well Storage situation and stored away  from direct sun light.

 

Our advantages:

 

1. Our factory was conducted Onsite assessment by TUV Rheinland from Germany. And

we have passed the ISO9001, Chinese health food GMP.

 

2. We inspect the manufacture process strictly and the quality can be controlled;

 

3. We supply high quality products, reasonable price, prompt delivery

 

4. Our best quality extract with natural and pure. No additives, organically grown