Hesperetin (CDDA007),China R&F PHARM price supplier

[The source of the plant] Citrus bitter orange.

[CAS No. ] 69097-99-0

[Molecular formula and molecular weight] C20H20O7; 372.38

[Main specification] 98% test by HPLC

[Pharmacology function]Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in HepG2 cells and reduces ApoB protein synthesis in a dose-dependent manner. The EC50 for these responses is approximately 50 µ M. 1 Hesperetin also inhibits histamine release from IgE-challenged RBL-2H3 cells, with a potency comparable to the commercial anti-allergy drug azelastine.