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What is St John's Wort?

St. John’s wort (Hypericum perforatum) is one of the most commonly used herbs in the United States. It is a shrubby perennial plant with bright yellow flowers. St. John's wort was named because the flowers were said to bloom for the first time around June 24, the birthday of St. John the Baptist. The word "wort" means "plant" in Old English.

 

Product Information

Basic Information

1. Product Name: St John's Wort P.E.

2. Botanical Source: Hypericum perforatum L.

 

 

3. Plant Part Used: Aerial Parts

4. Extraction Solvent: Grain Alcohol & Water

5. Active Ingredient: Hypericin

6. Test Method: HPLC/ UV

7. Specifications: 0.1% by HPLC, 0.3% by UV

8. Appearance: Brown-Black Fine Powder (For Reference Only)

9. Particle Size: 100% pass 80 Mesh

10. Shelf Life: 2 Years

11. Storage: Store in a Cool Dry Area. Do Not Freeze. Keep Away from Strong Direct Light and Heat.

 

Chemical Content

The major constituents of hypericum perforatum extract include naphthodianthrones, phloro glutinous and flavonoids. Naphthodianthrones contain hypericin, pseudohypericin, isohypericin, cyclopseudohpericin, protitpseudohypreicin, etc. Phloro glutinous contain hyperforin and adhyperforin. Flavonoids contain rutin, quercetin, etc. Chemical information of hypericin and pseudohypericin are as follows:

 

Chemical Name	CAS Number	Molecular Formula	Molecular Weight	Structural Formula
Hypericin	548-04-9	C 30 H 16 O 8	504.4432
Pseudohypericin	55954-61-5	C 30 H 16 O 9	520.4426

 

Traditional Use and Activity

St John's wort extract is widely used to treat depression, sometimes in an attempt to avoid adverse effects associated with prescription antidepressants. It is superior to placebo for treatment of mild to moderate depression.

The chemical compositions of St John's wort extract include naphthodianthrones, phloro glutinous and flavonoids. Many pharmacological activities appear to be attributable to hypericin and to the flavonoid constituents; hypericin is also reported to be responsible for the photosensitive reactions.

Extract of St. John's wort, applied to the skin, was a folk remedy for skin injuries, nerve pain, burns and hemorrhoids. Although the extract is sold in some herbal stores, creams are also available. Some are standardized to hypericin or hyperforin, which are thought to have anti-inflammatory and antibacterial effects. St. John's wort also contains tannins, naturally occurring compounds thought to relieve skin irritations, such as those resulting from minor cuts.  

 

Analysis Report Information

 

Item	Specification	Test Method
1. Physical Test
Identification	Positive	TLC
Appearance	Brown-Black Fine Powder	Visual
Odor	Characteristic	Organoleptic
Taste	Characteristic	Organoleptic
Mesh Size	100% pass 80 Mesh	80  Mesh Screen
2. Chemical Test
Ash	≤ 5.0%	2 g / 525 °C /3 hrs
Loss on Drying	≤ 5.0%	5 g / 105 °C /2 hrs
3. Marker compounds
Hypericin	≥ 0.1%	HPLC
Total St John's Wort	≥ 0.3%	UV-Vis
Hyperforin	≥ 3.0%	HPLC
4. Heavy metals
Total Heavy Metals	<10 ppm	Atomic Absorption
Lead (Pb)	< 2 ppm	Atomic Absorption
Cadmium (Cd)	< 1 ppm	Atomic Absorption
Arsenic (As)	< 2 ppm	Atomic Absorption
Mercury (Hg)	< 0.1 ppm	Atomic Absorption
5. Solvent Residues	< 0.05%	Gas Chromatography
6. Pesticide Residues	< 1 ppm	Gas Chromatography
666	< 0.1 ppm	Gas Chromatography
DDT	< 0.1 ppm	Gas Chromatography
7. Aflatoxins	≤ 0.2 ppb	HPLC
8. Microbiology
Total Plate Count	<1000 cfu/g	AOAC
yeast & Mould	<100 cfu/g	AOAC
E. Coli	Negative	AOAC
Salmonella	Negative	AOAC
Staphylococcus Aureus	Negative	AOAC

Notice: Items listed in this chart will be adjusted according to the actual situation. Any additional test items required by clients could be arranged, and there will possibly be additional charges. 

 

How We Get Extract Powder?

How we get extract powder is a long and detailed process. Once the raw material is procured, the process continues throughout a multitude of good manufacturing practices and stringent quality assurance controls. A brief flow chart of extraction process is as follows:  

 

 

 

About BZ BIOTECH

BZ BIOTECH is committed to providing high quality plant/herbal extracts, inspiring a love for plants and a respect for Mother Nature. Since it is founded, BZ Biotech has built trust with our customers the same way we produce our plant/ herbal products – with meticulous attention to detail and ethical business practices.                                                                                                      

At BZ BIOTECH, detail matters! A key ingredient in building and sustaining a successful business is repeat sales–especially to the same customers over many years. And this can only be achieved when our customers trust that our health-promoting plant/herbal extracts are consistently safe and effective – in other word, they actually work. How we get our plant/herbal extracts to "work" is a long and detailed process. Once the herbs are procured, the process continues throughout a multitude of good manufacturing practices and stringent quality assurance controls. This careful attention to detail assures our customers the trust that each and every product is produced correctly, batch after batch, each and every time. Another important ingredient to successful business is building trust with our customers through excellent customer service and by making sure each and every order is handled expeditiously so they consistently get exactly what they ordered, and on time.                                       

Get Herbal Extract Powder? Welcome to BZ BIOTECH!

 

Certification

 

 

Packaging

Package for greater than or equal to 25 Kg

Inner Package: Double Plastic Bags

Outer Package: Fiber Drum (Diameter: about 370 mm, Height: about 510 mm, Weight: about 3 Kg)

 

 

Package for less than 25 Kg

Inner Package: Double Plastic Transparent Self-Seal Bags

Outer Package: Sealed Aluminum Foil Bag

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