Loquat Leaf Extract 98% Ursolic Acid /cas No:77-52-1,China Xinshi price supplier

Loquat Leaf Extract 98% Ursolic Acid /cas No:77-52-1    

 

Product Name:	Loquat Leaf Powder extract
Latin Name:	Eriobotryajaponica (Thunb.)Lindl
Part of Plant Used:	Leaf
Active Ingredients:	Ursolic Acid 10%,20%, 25%,30%,90%,95%,98% by HPLC
Test Method:	HPLC
Appearance:	white or pale yellow Fine Powder
Odor:	Characteristic
CAS NO.:	77-52-1
Molecular weight:	456.71
Molecular formula:	C30H48O3

 

Introduction:  

Loquat leaf comes from the Loquat tree and helps to produce the Loquat fruit known as Eriobotrya japonica. It comes from the rose family and is sometimes called the Japanese plum leaf.  The Loquat tree is a moderately sized tree and can grow up to thirty feet. The Loquat leaves are evergreen and are five to twelve inches long and three to four inches wide. These beautiful leaves are glossed and dark-green.  Loquat leaves originate in the southeastern part of China and perhaps southern Japan, although some believe it was brought to Japan long ago by Chinese travelers. Legend has it that it has been grown in Japan for one thousand years.

 

Ursolic acid is a pentacyclic triterpene acid, used in cosmetics, that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor. As medicine, it is well tolerated and can be used topically and orally.

 

Ursolic acid is present in many plants, including apples, basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, prunes. Apple peels contain high quantity of ursolic acid and related compounds which are responsible for the anti-cancer activity of apple. Ursolic acid can also serve as a starting material for synthesis of more potent bioactive derivatives, such as anti-tumor agents.

 

Functions:

 

1. Pharmacological Action:  Medicinal plants containing ursolic acid have been used in folk medicine before it was known which constituents were responsible for their therapeutic effectiveness. Contemporary scientific research which LED to the isolation and identification of ursolic acid revealed and confirmed that several pharmacological effects, such as, anti-tumor, hepatoprotective, anti-inflammatory (oral and topical), anti-ulcer, antimicrobial, anti-hyperlipidemic and antiviral, can be attributed to ursolic acid1.

However, its anti-inflammatory (topical), anti-tumor (skin cancer), and antimicrobial properties are pertinent to the cosmetic industry.

 

2. Anti-aging agent:  Ursolic acid treatment improves the health of skin and hair. Ursolic acid and its derivatives form oil-resistant barriers on the skin and hair as they do in the waxy coating of fruits6. Ursolic acid has been used to treat photoaged skin because it prevents and improves the appearance of wrinkles and age spots by restoring the skin's Collagen bundle structures and its elasticity31. Concentrations of ursolic acid ranging from 0.01 to 50 mg have been reported for inclusion in skin treatment preparations.

 

3. Hair growth stimulant:  Ursolic acid and its isomer, oleanolic acid, have been used in to nics to enhance hair growth and prevent scalp irritation. Both triterpenoid compounds encourage hair growth by stimulating the peripheral blood flow in the scalp and activating the hair mother cells. They also furnish alopecia-preventing and dandruff-preventing effects.

 

4. Antimicrobial activity:  β Ursolic acid (triterpenoid sapogenin from the ursan group) inhibited the growth of several strains of staphylococci28. Numerous ursolic acid containing plants from the Lamiaceae family exhibited antibacterial/ fungal activity29. The minimal inhibitory concentration of Rosmarinus officinalis, Origanum majorana, and Lavandula officinalis were 500, 250, and 500 mg/cm3, respectively29. Ursolic acid also inhibited the growth of Microsporium lenosum and Candida albicans at 250 mg/mL30.

 

Applications:

 

 

1. Applied in food field, as raw materials of tea is easy to reduce phlegm;

2. Applied in pharmaceutical field may be it will become a new anti-cancer drug with low toxic;

3. Applied in cosmetic field, it can invigorate blood circulation and remove beverage.

 

 

Medicinal Use: 

 

Ursolic acid has medicinally action, both topically and internally. 

 

Ursolic acid is used in many cosmetic preparations for its anti -inflammatory, antitumor and antimicrobial properties.
Ursolic acid has antibacterial and antifungal activity. 
Ursolic acid has anti-inflammatory properties and is used in ointments to treat burns

 

 

Shelf Life: Two years under well storage situation and stored away from direct sun light

 

Storage: Stored in a cool and dry well-closed container, keep away from moisture and strong light/heat

 

  Technological Process:

 

  

Packing& Delivery:

 

Shelf life: 2 years when properly strored  
Storage: store in cool & dry place, avoid strong light and heat  
Packing: 25kg/ paper drum or according to customer's request  
Delivery: By UPS/DHL/TNT/EMS or by Air/ Sea as per Qty, within 3 days after we received customer's payment.

 

  

About us:

 

We specialized in manufacturing high quality and reliable raw material which are widely used in fields of food, health, cosmetic, pharmaceuticals, and others. We cooperate closely with some institutes and some universities and we have formed a technology and management team. At the same time, we take advantage of natural  pharmaceuticals resouces growing in the Qinba Mountain and develop different kinds of quality products to meet  market demand. 
 

Our Advantages:

 

We are professional manufacturer, with good quality;
We have professional testing staff;

We received GMP,ISO, .HACCP certificates.

 

Our Service:

 

Prompt Delivery;

Free samples can be offered;

Package can at your option;

Prompt shipment with professional documents;

Mixed container, different items can be mixed in one container.