| ≥1 piece |
Loquat extract
1. 100% natural
2. GMP certified manufacture
3.35%, 90%, 98% Ursolic acid
4. Free of solvent residue
What's Ursolic acid?
Ursolic acid, a carboxylic acid present in a wide variety of plants in the form of a free acid or an aglycone of triterpene saponins.It is also known as urson, prunol, micromerol, and malol, is a pentacyclic triterpenoid compound which naturally occurs in a large number of vegetarian foods, medicinal herbs, and plants1,2. For a long time, it was considered to be pharmacologically inactive3. Thus, ursolic acid and its alkali salts (e.g. potassium or sodium ursolates) were exclusively used as emulsifying agents in pharmaceutical, cosmetic, and food preparations3,4. However, upon closer examination, ursolic acid was found to be medicinally active both topically and internally1. Its anti-inflammatory, antitumor (skin cancer), and antimicrobial properties make it useful in cosmetic applications1.
Ursolic acid, also known as urson, prunol, micromerol, and malol, is a pentacyclic triterpenoid compound which naturally occurs in a large number of vegetarian foods, medicinal herbs, and other plants1,2. For a long time, it was considered to be pharmacologically inactive3. Thus, ursolic acid and its alkali salts (e.g. potassium or sodium ursolates) were exclusively used as emulsifying agents in pharmaceutical, cosmetic, and food preparations3,4. However, upon closer examination, ursolic acid was found to be medicinally active both topically and internally1. Its anti-inflammatory, anti-tumor (skin cancer), and antimicrobial properties make it useful in cosmetic applications1.
Notwithstanding its numerous cosmetic properties, ursolic acid is an ideal cosmetic ingredient because its overall toxicity (both chronic and acute) is low. It is not a primary irritant or sensitizer. In fact, it has been termed dermatologically innocuous4.
Product Name: Ursolic acid
Plant sources:
- leaves of Eriobotrya japonica Thunb.
- Leaves of Rosmarinus officinalis.
- Dried ripe fruits of Ligustrum lucidum Ait.
Active Ingredients: Ursolic acid
Appearance: Brown powders, or white crystalline and powders (content ≥90%)
Specifications:
- 35%, 90%, 98%
- Any other specifications can be customized.
Test Method: HPLC (External standard method)
Quality Standard: Enterprise standard
Packing: 1kg/bag, 5kg/bag, or 25kg/drum or Customized .
Our Advantage:
- Unique technique for extraction of specific active ingredients, other chemical substances are not introduced in the production process;
- Unique enrichment process of active ingredient, without introducing additional risky material.
What are Health Benefits?
Ursolic acid treatment improves the health of skin and hair. Ursolic acid and its derivatives form oil-resistant barriers on the skin and hair, just as they form the waxy coating of fruits. Ursolic acid has been used to treat photoaged skin, because it inhibits the appearance of wrinkles and age spots by restoring the skins Collagen bundle structures and elasticity. Ursolic acid inhibits the action of elastase enzyme in the skin, thereby preventing the enzyme from attacking structural proteins. Ursolic acid also inhibits the inflam-matory enzymes cyclooxygenase and lipoxygenase.
1.Pharmacological Action:
Medicinal plants containing ursolic acid have been used in folk medicine before it was known which constituents were responsible for their therapeutic effectiveness. Contemporary scientific research which led to the isolation and identification of ursolic acid revealed and confirmed that several pharmacological effects, such as, anti-tumor, hepatoprotective, anti-inflammatory (oral and topical), anti-ulcer, antimicrobial, anti-hyperlipidemic and antiviral, can be attributed to ursolic acid1. However, its anti-inflammatory (topical), anti-tumor (skin cancer), and antimicrobial properties are pertinent to the cosmetic industry.
2.Anti-aging agent:
Ursolic acid treatment improves the health of skin and hair. Ursolic acid and its derivatives form oil-resistant barriers on the skin and hair as they do in the waxy coating of fruits6. Ursolic acid has been used to treat photoaged skin because it prevents and improves the appearance of wrinkles and age spots by restoring the skin's collagen bundle structures and its elasticity31. Concentrations of ursolic acid ranging from 0.01 to 50 mg have been reported for inclusion in skin treatment preparations 32-33.
3.Hair growth stimulant:
Ursolic acid and its isomer, oleanolic acid, have been used in to nics to enhance hair growth and prevent scalp irritation26,27. Both triterpenoid compounds encourage hair growth by stimulating the peripheral blood flow in the scalp and activating the hair mother cells. They also furnish alopecia-preventing and dandruff-preventing effects27.
4.Antimicrobial activity:
β ursolic acid (triterpenoid sapogenin from the ursan group) inhibited the growth of several strains of staphylococci28. Numerous ursolic acid containing plants from the Lamiaceae family exhibited antibacterial/ fungal activity29. The minimal inhibitory concentration of Rosmarinus officinalis, Origanum majorana, and Lavandula officinalis were 500, 250, and 500 mg/cm3, respectively29. Ursolic acid also inhibited the growth of Microsporium lenosum and Candida albicans at 250 mg/mL30.
5.Anti-inflammatory activity:
Ursolic acid is a potent anti-inflammatory agent. Thus, it has been recommended for use in burn ointments4. It not only inhibits human leucocyte elastase(HLE), but also 5-lipoxygenase and cyclooxygenase activity21, 22. Ursolic acid (1.0 mg/ear) inhibited TPA-induced mouse ear edema by 72.4%23. Hirota and coworkers24 determined that 200 mg and 50 mg applications of ursolic acid inhibited 12-O-hexadecanoyl-16-hydroxyphorbol-13-acetate (HPPA) - induced inflammation by 49% and 33%, respectively. In addition, it inhibited concanavalin.
Effects:
- Antioxidant
- anti-hepatitis;
- antibacterial, antiviral
- Lowering blood glucose level
- antiulcer
- anti-cancer
- Sedation
Applications:
- Functional food additive & health supplement
- Pharmaceuticals
- Cosmetics & personal care products
Hunan Zhengdi Biological Resources Development Co.,Ltd. concentrates on the high-efficient comprehensive development of plant resources and their deep-processing products. We are a manufacturer, a high-tech enterprise with enormous experience in research and development, as well as abundant plant resources.
Focusing on R&D and keep improving
We have made a breakthrough on processing technology in order to meet the limits of microorganism and heavy metal content. We have experiences on R&D of medicine and health food for over 10 years, and our advantage are research on preparation technology, quality standard and study on general pharmacology & toxicology.
O utstanding advantages on controlling the resources
We have own planting base of herbal medicines and cooperate with professional herbal medicine cultivation institutions. The cultivation is strictly according to the requirements of Chinese GAP standard. To ensure the raw material quality, harvest season, field processing, storage and transportation are also strictly controlled.
Outstanding achievements on quality management
Our company has built the GMP plant completely complying with Good Manufacture Practice in Hunan Zhanda Taikang Pharmaceutical Co., Ltd. and has the relevant Chinese drug GMP certificate.
Production is strictly conducted according to Good Manufacture Practice. All the procedures are regulated by relevant GMP documents, from the purchase of raw material to sales of the finished product, to ensure the traceability of the whole production process in order to guarantee the product quality.
Leading talent pool in the industry
Our Management team has abundant pharmaceutical professional background, and main supervisory technical staffs have application and registration experiences of medical products and health-related products for ten years and can accurately grasp the requirements of policies, regulations and technical principles of medical products and health-related products.
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| Type: |
Herbal Extract
|
Variety: |
Loquat extract
|
Form: |
Powder,fine powder
|
| Part: |
Leaf
|
Extraction Type: |
Solvent Extraction
|
Packaging: |
Drum
|
| Place of Origin: |
Hunan China (Mainland)
|
Grade: |
Food grade,Pharmaceutical and food grade
|
Brand Name: |
Zhengdi
|
| Model Number: |
ZDE-10
|
Function: |
Antioxidant,anti-hepatitis,antibacterial, antiviral,antiulcer,cancer
|
Latin name of Plant: |
Eriobotrya japonica Thunb.
|
| Active ingredients: |
Ursolic acid
|
Assay: |
35%, 90%, 98%
|
Appearance: |
Brown powders, or white crystalline and powders (content ≥90%)
|
| Applications: |
Pharmaceuticals, Cosmetics & personal care products
|
Molecular formula: |
C30H48O3
|