| ≥1 piece |
|
Items |
Specifications |
|
Appearance |
Grayish-yellow or light yellow hygroscopic powder |
|
Taste & Odor |
Tasteless, odorless |
|
Solubility |
Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides |
|
Identification |
HPLC |
|
Iodine content |
≤0.1% |
|
Water |
≤6.0% |
|
Sulphated ash |
≤0.2% |
|
Heavy metals |
≤20 ppm |
|
Related substances(HPLC) |
Acetoisovanillone≤0.5% (Impurity A) Isorhoifin≤3.0% (Impurity C) 6-iododiosmin≤ (Impurity D] Linarin≤3.0% (Impurity E) Diosmetin≤2.0% (Impurity F) Any other impurity≤0.4% Total impurities(different than hesperidin)≤5.5% |
|
Particle size (Micronized) |
95% below 5 microns |
|
Diosmin-Hesperidin ratio |
90/10(W/w) |
|
Assay (HPLC) |
Diosmin 81.0% – 89.0.0% (anhydrous substance) Hesperidin: 8.0%--11.0% (anhydrous substance) |