Sophora Root Extract,98% Matrine,China FINESKY price supplier

Bitter sophora is a genus of about 45 species of small trees and shrubs in the subfamily Faboideae of the pea family, Fabaceae. The species are native to southeast Europe, southern Asia, Australasia, the islands of the Pacific Ocean and western South America. The generic name is derived from sophera, an Arabic name for a pea-flowered tree.

Matrine and oxymatrine are the two major alkaloid components found in bitter sophora root. They are obtained primarily from Sophora japonica (kushen), but also from Sophora subprostrata (shandougen), and from the above ground portion of Sophora alopecuroides. An intensive investigation into the pharmacology and clinical applications of these alkaloids has gone on for the past decade and remains one of the focal points of Chinese medical research. The main clinical applications of bitter sophora root Extract are treatment of people with cancer, viral hepatitis, cardiac diseases, and skin diseases. 

In China, the alkaloids are often given by injection, but this method of administration is not acceptable in the West, so oral dosing is used here instead. When taken orally, much of the oxymatrine is converted to matrine. To get high blood levels of oxymatrine, it must be given by injection. However, it is unclear whether oxymatrine is clinically more effective than matrine. Chinese researchers have also used the alkaloids in capsule form, with results that appear similar to the injection. Sophora is also administered in complex formulas made as decoctions and taken orally.