| ≥1 piece |
white willow bark extract 15%
| ITEM | STANDARD |
| Appearance | Brown Powder |
| Odor | Characteristic |
| Sieve analysis | 100% pass 80 mesh |
| Assay:(Salicin HPLC) | 15% |
| Loss on Drying Residue on Ignition | ≤5.0% ≤5.0% |
| Bulk Density | 40-55g/100mL |
| Extract Solvent | Alcohol & Water |
| Heavy Metal | ≤10ppm |
| As | ≤2ppm |
| Pb | ≤1ppm |
| Cd | ≤1ppm |
| Hg | ≤1ppm |
| Residual Solvents | Eur.Pharm. |
| Total Plate Count | ≤10000cfu/g |
| yeast & Mold | ≤1000cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
white willow bark extract 25%
| ITEM | STANDARD |
| Appearance | Brown Powder |
| Odor | Characteristic |
| Sieve analysis | 100% pass 80 mesh |
| Assay:(Salicin HPLC) | 25% |
| Loss on Drying Residue on Ignition | ≤5.0% ≤5.0% |
| Bulk Density | 40-55g/100mL |
| Extract Solvent | Alcohol & Water |
| Heavy Metal | ≤10ppm |
| As | ≤2ppm |
| Residual Solvents | Eur.Pharm. |
| Total Plate Count | ≤10000cfu/g |
| Yeast & Mold | ≤1000cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
Salicin is analcoholic β-glucoside.Salicin is an anti-inflammatory agent that is produced from willow bark.
It isalso found in castoreum, which was used as an analgesic, anti-inflammatory, andantipyretic. The activity of castoreum has been credited to the accumulation ofsalicin from willow trees in the beaver's diet, which is transformed tosalicylic acid and has an action very similar to aspirin.
Salicinis closely related in chemical make-up to aspirin. When consumed, the acetalicetherbridge is broken down. The two parts of the molecule, glucose andsalicylic alcohol, then are metabolized separately. By oxidizing the alcoholfunction the aromatic part finally is metabolized to salicylic acid.
Salicinelicits bitterness like quinine, when consumed.
Alkalinecleavage of the glucoside populin produces benzoate and salicin.