Product name: ALpha Lipoic Acid
IUPAC name: (R)-5-(1, 2-dithiolan-3-yl)pentanoic acid
Synonyms: DL-Thioctic acid; DL-6, 8-Dithiooctanoic acid; 5-(Dithiolan-3-yl)valeric acid; α -lipoic acid; Thioctic acid; 6, 8-dithiooctanoic acid
C. A. S #: 1077-28-7
Molecular formula: C8H14O2S2
Molecular weight: 206.33
Melting point: 58-63° C
Boiling point: 160-165° C
Alpha-Lipoic acid contains not less than 99.0 percent and not more than 101.0 percent of C8H14O2S2, calculated on the dried basis.
Characteristic: Yellow crystalline powder, almost tasteless.
Quality Standards: USP30;
Assay: 99.00% Min. (by HPLC);
Specific Optical Rotation(C=1, Ethanol): +110~+120°
Water solubility: Soluble in benzene, ethanol, ethyl ether, chloroform and other organic solvents, but also soluble in water.
Function and Usage: α -lipoic acid is a vitamin drugs, limited physical activity in its dextral, basically no physical activity in its L - Lipoic acid, and no side effects. It is always used for acute and chronic hepatitis, Liver cirrhosis, hepatic coma, fatty liver, diabetes, Alzheimer's disease, and applies as an antioxidant health products.
Lipoic acid (LA), also known as α -lipoic acid and alpha lipoic acid (ALA) is an organosulfur compound derived from octanoic acid. LA contains two vicinal sulfur atoms (at C6 and C8) attached by a disulfide bond and is thus considered to be oxidized (although either sulfur atom can exist in higher oxidation states). The carbon atom at C6 is chiral and the molecule exists as two enantiomers R-(+)-lipoic acid (RLA) and S-(-)-lipoic acid (SLA) and as a racemic mixture R/S-lipoic acid (R/S-LA). Only the R-(+)-enantiomer exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Endogenously synthesized RLA is essential for life and aerobic metabolism. Both RLA and R/S-LA are available as over-the-counter nutritional supplements and have been used nutritionally and clinically since the 1950s for various diseases and conditions. LA appears physically as a yellow solid and structurally contains a terminal carboxylic acid and a terminal dithiolane ring.