| ≥1 piece |
Product Description
broccoli extract
Specificati: 10: 1 and Sulforaphen(2%)
Action:
1)Broccoli Extract can be prevent the cancer.
2)Broccoli Extract has has already been shown to boost liver and skin cells' detoxifying abilities.
Broccoliextract has been shown to prevent neoplastic transformation by carcinogens in mammalian cells by inducing detoxification enzymes. To test whether broccoli could have other anticancer properties, the ability of a broccoli extract to inhibit the growth of three transformed mammalian cell lines was examined. The proliferation of MCF-7 human breast cancer cells, H-ras-transformed MCF-7 cells, and v-ras-transformed RAT1 fibroblast cells was measured in the presence of the broccoli extract and also compared to the proliferation of non-transformed cultured human lymphocytes.
Broccoli extract was found to inhibit significantly the growth of all three transformed cell lines in a dose-dependent form, whereas non-transformed human lymphocytes were found to be initially induced, and later only moderately inhibited. Comparison of the extract's effect on the three transformed cell lines suggested that ras-transformed cells were more sensitive to inhibition by broccoli extract. Since induction of adenylate cyclase was recently reported to inhibit mammalian cells by down-regulating the ras growth pathway, RAT1 cells treated with broccoli extract were assayed for adenylate cyclase activity using a cAMP enzyme immunoassay. Broccoli was found to induce adenylate cyclase during the exponential growth of the RAT1 cells. In summary, these investigations identify broccoli as a specific inhibitor of transformed cell growth, possibly through induction of adenylate cyclase, and suggests potential therapeutic properties of the extract