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Diosmin CAS-No.: [520-27-4]
?? Specification: EP6.0
?? EDMF in CTD format
?? Chemical Name
7 - [[ 6- O -(6- D e o xy - α -L- ma n nop y r a n os y l ) - β -D - gl u c o py ranos yl ] ox y ] - 5- hy dro xy - 2-(3-hy d roxy-4- m ethoxyph e ny l )-4 H - 1 - b e n z o pyr an - 4 -o n e.
?? Structural formula
?? Molecular formula
C 28 H 32 O 15
?? Relative molecular weight
609
?? Botanical Source:
citrus AurantiumL.
?? Description
Diosmin is a biogenic amine derived by extracting hesperidin from citrus aurantium L ., followed by conversion of hesperidin to diosmin. Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties. Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.
?? Appearance
Greyish-yellow or light yellow hygroscopic powder.
?? Solubility
Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides