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factory supply cognitive improvment with Citrus Limon extract diosmetin .diosmin.diosmetin 98%
Product Name : Diosmetin 98%
Botanical source : Citrus Limon (L.) Burm
Specification : 98%
CAS NO. 520-34-3
Appearance : light yellow fine powder
The Chemical name is 3’,5,7-trihydroxy-4’-methoxyflavone
The appearance is light yellow powder .
Melthing point 256~258℃
Molecular formula: C16H12O6
Molecular weight: 300.26
It can souble in methanol ,ethanol and other solvents.
Diosmetin widely exsist in nature, mainly in the form of free type or Glucoside type .
It can be found in chrysanthemum, spearmint, Valeriana jatamansi and Lemon .
Not only the flavonoids are an important part of People daily diet, but Also Diosmetin has the function of prevention of cancer which is as the deitary flavonoids in the chemical prevention of cancer is a hot topic of domestic and foregin schloars in recent years.
How diosmetin produce effect to our body ?
The main biological activity of geraniol and its Mechanism
It has stronggest antioxidant ,antibacterial,anti-tumor and estrogen-like effect,the mechanism involves the removal of free radicals, induction of apoptosis and inhibition of intracellular signal transmission. As a CYP1A enzyme activity inhibitor .
A. Antioxidant
Alzheimer's disease is the most common cognitive dysfunction in the elderly population. Over-production and accumulation of beta-amyloid peptide (Aβ) is considered to be the leading cause of Alzheimer's disease. Advanced glycation end products (AGEs) have a close interaction with Aβ, whereas AGEs and their receptors use intracellular reactive oxygen species to transmit signals. ChandlerD et al. [14] have shown that geranyl has the ability to remove these reactive oxygen species and can delay the production of AGEs and their receptors and are therefore considered to be a natural antioxidant.