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4-hydroxyisoleucine may amplify carbohydrate-induced insulin secretion. Therefore, supplements containing 4-hydroxyisoleucine allows athletes to load up on nutrient stores at a cellular level. This may include mass building compounds such as creatine, carbohydrates and protein. What's more, 4-hydroxyisoleucine may also increase the receptivity of muscle cells to insulin, thus increasing nutrient storage in muscles while deterring storage to fat cells. Whether you are shooting for greater speed, strength, or muscular development, 4-hydroxyisoleucine can help!