| ≥1 piece |
Product name : Naringin
Botanical source : Citrus grandis (L.)Osbeck
Assay:98%
Appearance: light yellow fine powder
：HPLC
CAS NO. 10236-47-2
Molecular formula : C27H32O14
Molecular weight : 580.53
Extract solvent : Ethanol
Solubility : soluble in hot water
Heavy metals: <10ppm
Pesticides residue: Meet EP standards < Reg.(EC)No.1993/2015>
GMO: Non-GMO
Irradiation: Non-Irradiation
Brief Introduction of Grapefruit seed extract Naringin
Naringin belongs to the group of flavonoids. Pure naringin is a yellowish powder.
Naringin is a flavanone-7-O-glycoside between the flavanone naringenin and the disaccharide neohesperidose. The flavonoid naringenin occurs naturally in citrus fruits, especially in grapefruit, where naringin is responsible for the fruit's bitter taste. .
Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavonone naringenin in humans.
Narinigin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticarcinogenic activity, and inhibition of selected cytochrome P450 enzymes including CYP3A4 and CYP1A2, which may result in several drug interactions in-vitro.
So how is the grapefruit seed extract Naringin produce effect to our body ?
Naringin and its aglycone naringenin belong to this series of flavonoids and were found to display strong anti-inflammatory and antioxidant activities. Several lines of investigation suggest that naringin supplementation is beneficial for the treatment of obesity, diabetes, hypertension, and metabolic syndrome. A number of molecular mechanisms underlying its beneficial activities have been elucidated. However, their effect on obesity and metabolic disorder remains to be fully established. Moreover, the therapeutic uses of these flavonoids are significantly limited by the lack of adequate clinical evidence. This review aims to explore the biologic activities of these compounds, particularly on lipid metabolism in obesity, oxidative stress, and inflammation in context of metabolic syndrome.