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grape seed extract is an important source of one of nature's most potent antioxidants, proanthocyanidins. Research has shown that proanthocyanidins serve as free radical scavengers. Used extensively in Europe, grape seed extract is rich in flavonoids, phytochemicals that have antioxidant properties some consider even greater than the old standbys vitamin C and vitamin E. antioxidants are believed to prevent and control numerous ailments by safeguarding cells against the ravages of unstable oxygen molecules called free radicals. Grape Seed Extract may benefit from the extract's ability to block the release of this pain- and inflammation-causing chemical. Grape seed extract effectively penetrates cell membranes throughout the body with its antioxidant properties. It can even cross into the brain (traversing the blood-brain barrier) to protect brain cells from free-radical damage.