Active ingredients: Hesperidin
Test method:HPLC
Appearance: light brown powder
CAS No.: 520-26-3
Formula: C 28 H 34 O 15
Molecular Weight: 610.57
EINECS: 208-288-1
Density: 1.653 g/cm 3
Melting Point: 250-255 °C (dec.)(lit.)
Boiling Point: 930.067 °C at 760 mmHg
Risk Codes: 22-36/37/38
Safety: 22-24/25-36/37/39-27-26
Application: Applied in dietary supplements,pharmaceutical or cosmeticeuticals
a) Hesperidin is a bioflavonoid. Bioflavonoids are water-soluble nutrients that are found in some fruits -- especially Citrus -- and various leafy green vegetables.
b) Hesperidin, along with other bioflavanoids, can improve the health of capillaries and connective tissues. Because of this, it has been noted to help with bruising, varicose veins, and fragile capillaries.
c) Other benefits include a purported ablility to alleviate hay fever and other such allergies. Some studies suggest bioflavanoids like hesperidin and quercitin do this by inhibiting the release of histamine
Various preliminary studies reveal novel pharmaceutical properties, none of which has been confirmed as applicable to humans. Hesperidin reduced cholesterol and blood pressure in rats. In a mouse study, large doses of hesperidin decreased bone density loss. Another animal study showed protective effects against sepsis. In vitro and in laboratory research, hesperidin has anti-inflammatory effects. Hesperidin is also a potential sedative , possibly acting through opioid or adenosine receptors . Hesperidin exhibited pronounced anticancer activity against some selected human carcinoma cell lines .Some in vitro results applied only to the aglycone form. Hesperidin also showed potential to penetrate the blood–brain barrier in an in vitro model.Hesperidine and its synthetic derivative diosmin , components of the drug Daflon , can have a conservative role against the symptoms of varicose veins