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(2-Hydroxypropyl)-β-cyclodextrin
CAS Number: 128446-35-5
EC Number: 420-920-1
PubChem Substance ID: 24895425
e solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.