| ≥1 piece |
Common Name: Silybin
CAS number: 22888-70-6
Active ingredients: Silybin is the mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio. Both in vitro and animal research suggest that Silybin has hepatoprotective (antihepatotoxic) properties that protect Liver cells against toxins.
Botanical Name: Silybum marianum
Plant Part: Seeds of S. marianum
Purity: ≥98% ( mixture of two diastereomers, silybin A and silybin B)
Supplied As: crystalline Yellow powder.
Solvent: Ethanol, DMSO, and Dimethyl formamide
Country of Origin: China
Product Information:
Silybin is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, silybin should first be dissolved in DMF and then diluted with the aqueous buffer of choice. Silybin has a solubility of approximately 0.5 mg/ml in a 1:9 solution of DMF:PBS (pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.
Range of application:
Silybin is the major flavonolignan from the extracts of Milk Thistle seed, S. marianum. The whole extract, known as silymarin, has been found to protect the liver from both acute and chronic toxicity and injury.
Silybin blocks the production of superoxide in PMA-activated rat Kupffer cells with an EC value of around 100 µM.
Silybin also blocks the synthesis of leukotriene B by these same cells with an IC50 value of about 15 µM.
Thus, part of the protective effects of silybin could be due to 5-lipoxygenase inhibition.
Storage: ≥2 years at -20°C
Packing: 25kg barrel/ / Can or Depends on requirements.
Our Advantages:
We specialize in plant extract, amino acid, API & intermediates, food additive, nutraceutical supplement etc. Our businesses have already extended to more than 50 countries that separately located in Europe, America, East & Southeast Asia, Africa and Oceania. We have: extensive experience, professional R&D and sales team, strict quality control, competitive price.
Product customization: According to customer quality standards for customization**