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Carnosine
Description:
1) L-Carnosine (beta-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.
2) L-Carnosine and carnitine were discovered by Russian chemist V.Gulevich.Researchers in Britain,South Korea,Russiaand other countries have shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturatedaldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. Carnosine is also a zwitterion, a neutral molecule with a positive and negative end.
3) Like carnitine, carnosine is composed of the root word carn, meaning flesh, alluding to its prevalence in animal protein. A vegetarian (especially vegan) diet is deficient in adequate carnosine, compared to levels found in a standard diet.
Carnosine can chelate divalent metal ions.
4) L- Carnosine can increase the Hayflick limit in human fibroblasts,as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.
Application：
1.New food additives
Carnosine has a significant inhibitory effect on lipid oxidation caused by free radicals and metal ions, and carnosine has the effect of inhibiting fat oxidation and protecting flesh color in meat processing. Carnosine and phytic acid are resistant to beef oxidation. It can improve the color of the meat and improve the oxidative stability of skeletal muscle, and has a synergistic effect with vitamin E, which can promote human ingestion.
2. Medical industry protection agent
In surgery, carnosine promotes wound healing, especially for oral medications for surgical treatment. Carnosine can enhance the Heifelick limit of human fibroblasts and the rate of telomere shortening. The maintenance of telomeres may be beneficial to the growth of some potential cancers, so carnosine is also considered a medical protective agent.
Functions:
1) L-Carnosine is the most effective anti-carbonylation agent yet discovered. (Carbonylation is a pathological step in the age- related degradation of the body proteins. )Carnosine helps to prevent skin collagen cross-linking which leads to loss of elasticity and wrinkles
2) L-carnosine powder also acts as a regulator of zinc and copper concentrations in nerve cells, helping to prevent overstimulation by these neuroactive in the body substantiates all of the above and other studies have indicated further benefits.
3) L-Carnosine is a SuperAntiOxidant that quenches even the most destructive free radicals: The hydroxyl and the peroxyl radicals, superoxide, and singlet oxygen. Carnosine helps to chelate ionic metals(flush toxins from the body). adding volume to the skin.
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