L-Valine
Abbreviation: L-Val
CAS Number: 72-18-4
Chemical Name: (2S)-2-Amino-3 -Methylbutanoic Acid
Chemical Formula: C5H11NO2
Molecular Weight: 117.1500
Property: White crystals or crystalline powder, Soluble in water.
Valine is a branched-chain amino acid (BCAA) that works with the other two BCAAs, isoleucine and leucine, to promote normal growth, repair tissues, regulate blood sugar, and provide the body with energy. Valine helps stimulate the central nervous system, and is needed for proper mental functioning.
Valine helps prevent the breakdown of muscle by supplying the muscles with extra glucose for energy production during intense physical activity. Valine also helps remove potentially toxic excess nitrogen from the Liver, and is able to transport nitrogen to other tissues in the body as needed. Valine may help treat liver and gallbladder disease, as well as damage to these organs caused by alcoholism and drug abuse. Valine may help treat or even reverse hepatic encephalopathy, or alcohol-related brain damage.
Valine is an essential amino acid, which means that it cannot be manufactured in the body and must be obtained through dietary sources. Natural sources of valine include meats, dairy products, mushrooms, peanuts, and soy protein. Although most people get enough valine from their diet, there have been recorded cases of valine deficiency. Maple syrup urine disease (MSUD) is caused by the inability to metabolize leucine, isoleucine, and valine. The disease is so named because urine from affected people smells like maple syrup. A deficiency of valine may also affect the myelin covering of the nerves, and cause degenerative neurological conditions.
Applications:
Amino acid infusion, comprehensive amino acid preparation;
Due to impaired liver function, Advanced cirrhosis is easy to form hyperinsulinemia, resulting in reduced branched-chain amino acids in blood , branched-chain amino acids and aromatic amino acid ratio goes down from normal 3.0-3.5 to 1.0-1.5. So branched chain amino acids like Valine are commonly used in injection in treatment of liver failure and other diseases, also used to accelerate the wound healing drugs;Nutritional supplements